Ryan welcomes WPEngine CTO Ramadass Prabakar to the show to chat about what happens—and what we should do—when agents start acting like humans online, how our internet is evolving to serve both human and agentic experiences from the same interface, and what we can do to differentiate and protect human actions online from malicious bot activity.
Live from Snowflake Summit, Ryan talks with Snowflake’s Head of Developer Experience Umesh Unnikrishnan about the industry-wide shift from “vibe coding” for quick prototypes to agentic engineering for enterprise-ready software, how enterprises can scale governance with guardrails like human-in-the-loop approval and control layers that go beyond the underlying LLM, and why Umesh predicts all developers will become someday become full-stack builders.
Recorded at Microsoft Build, Ryan welcomes Sarah Bird, Microsoft’s Chief Product Officer for Responsible AI, about how we can build and use AI responsibly with the NIST approach, why most irresponsible AI comes from experimentation without thought of impact, and how Microsoft is researching thoughtful human/AI workflow design to reduce unnecessary escalation.
Ryan is joined by Nancy Wang, CTO of 1Password, to discuss the security challenges local agents present, how enterprises can create robust governance of credentials through zero-knowledge architecture, and the implications of agent intent and misuse in a world where AI agents are becoming more and more integrated into everyday applications.
Ryan is joined on the podcast by Confluent’s AI Entrepreneur in Residence, Sean Falconer, to discuss the growing need for standards for AI agents, the emerging Model Context Protocol and agent-to-agent communication, and what we can learn from early web standards while AI continues to evolve.
Ryan welcomes Illia Polosukhin, co-author of the original "Attention Is All You Need" Transformers paper and co-founder of NEAR, on the show to talk about the development and impact of the Transformers model, his perspective on modern AI and machine learning as an early innovator of the tech, and the importance of decentralized, user-owned AI utilizing the blockchain.
Maryam Ashoori, Head of Product for watsonx.ai at IBM, joins Ryan and Eira to talk about the complexity of enterprise AI, the role of governance, the AI skill gap among developers, how AI coding tools impact developer productivity, what chain-of-thought reasoning entails, and what observability and monitoring look like for AI.
Two interviews for the price of one, direct from HumanX 2025! Ryan sits down with Raj Patel, AI transformation lead at Holistic AI, and then chats with Audioshake cofounder and CEO Jessica Powell.
