AI is not a linear process. To scale effectively, engineering leaders must account for varied edge cases, presenting a new set of challenges.

Katja Skafar, Susi O'Neill

In today’s episode, Ryan sits down with Richard “Spencer” Schaefer, cofounder and CTO of Lunar Analytics and a federal AI officer, and Caroline Zhang, cofounder and CTO of Knowtex, which provides AI-powered voice technology to automate workflows. They talk about safeguarding patient privacy, how AI changes doctor-patient interactions and healthcare delivery, the challenges inherent in rolling out AI technology, and the importance of quality data to fuel AI initiatives. Also included: a chat with Jeff Berkowitz, cofounder and CEO of Delve Deep Learning.

Eira May

Ryan chats with Amr Awadallah, founder and CEO of GenAI platform Vectara about how retrieval-augmented generation (RAG) has advanced, why fact-checking and accurate data are essential in building AI applications, and how Vectara’s Mockingbird model seeks to minimize hallucinations.

Eira May

On this episode of Leaders of Code, Maureen Makes, VP of Engineering at Recursion, discusses AI's role in drug discovery, scaling and integration challenges, and the importance of innovation in achieving the high standards desired.

Ryan welcomes Tomasz Tunguz of Theory Ventures back to the podcast to talk about the intersection of AI and venture capital, the implications of AI on the labor market, and the future of AI applications.

Eira May

AI is changing how we think about coding. While tools evolve, critical thinking, problem-solving, and creativity remain the essential skills for top developers.

Katja Skafar, Susi O'Neill

At HumanX 2025, Ryan sat down with HumanX CEO Stefan Weitz and Crunchbase CEO Jager McConnell to talk about where the money is in the AI space, where most enterprise AI strategies fall short, how companies can build business models when AI tech is evolving so quickly, and why this is AI’s microservices moment.

Eira May

Data has always been key to LLM success, but it's becoming key to inference-time performance as well.

Or Lenchner

Two interviews for the price of one, direct from HumanX 2025! Ryan sits down with Raj Patel, AI transformation lead at Holistic AI, and then chats with Audioshake cofounder and CEO Jessica Powell.

Eira May

Deepak Singh, VP of Developer Agents and Experiences at AWS, helps Ryan break down the hype around agentic AI in software development. They cover the definition and real-world functionality of AI agents, how developers can integrate them into existing workflows, and the importance of establishing guardrails to ensure trust and security in agentic AI.

Eira May

In this episode of Leaders of Code, host Ben Popper, Stack Overflow CEO Prashanth Chandrasekar, and GitLab Field CTO Lee Faus explore how GenAI is reshaping software development practices.

Ryan speaks with Edo Liberty, Founder and CEO of Pinecone, about building vector databases, the power of embeddings, the evolution of RAG, and fine-tuning AI models.

Eira May

Stack Overflow CEO Prashanth Chandrasekar sat down with Ryan at HumanX 2025 to talk about how Stack is integrating AI into its public platform, the enormous importance of a high-quality knowledge base in your AI journey, how AI tools are empowering junior developers to build better software, and much more.

Eira May

Tillman Elser, AI/ML lead at Sentry, joins Ryan for a conversation about improving error monitoring with AI and ML. They talk through the challenges of analyzing stack traces, the innovative use of embeddings to improve error grouping, the trial-and-error process of developing algorithms, and where Sentry’s AI capabilities are headed next.

Eira May

In the first episode of our new podcast series, Leaders of Code, we sat down with Don Woodlock, Head of Global Healthcare Solutions at InterSystems, and Stack Overflow CEO Prashanth Chandrasekar to discuss data strategy's critical role in AI development.

Katja Skafar, Susi O'Neill

Some high-level takeaways, with more to come.

Eira May

Lisbeth Kaufman, Head of Climate Tech at AWS, sits down with Ryan to talk about her work helping climate tech startups get off the ground and the role startups can play in addressing the climate change crisis. She highlights a few projects to get excited about, including ones focused on fusion energy and sustainable agriculture.

Eira May

In our very first episode, Stack Overflow CEO Prashanth Chandrasekar talks to Don Woodlock, Head of Global Healthcare Solutions at InterSystems, about the challenges in their AI journey and the critical role of a robust data strategy in any successful AI initiative.

Ryan welcomes Zach Lloyd, founder and CEO of Warp, to the show to talk about reimagining the terminal. They also discuss why Warp was built in Rust (“it’s definitely harder”), how AI is transforming developer tools, and what Zach (formerly a principal engineer at Google) learned building Docs and Sheets.

Eira May

Jeremy “Jezz” Kellway, VP of Engineering for Analytics and Data & AI at EDB (Enterprise Database), joins Ryan for a conversation about Postgres and AI. They unpack how Postgres is becoming the standard database for AI applications, the importance of managing unstructured data, and the implications of data sovereignty and governance in AI.

Eira May

Olga Beregovaya, VP of AI at Smartling, joins Ryan and Ben to explore the evolution and specialization of language models in AI.

Eira May

How Diffblue leverages machine learning techniques to write effective unit tests.

Eira May

Ken Stott, Field CTO of API platform Hasura, tells Ryan about the data doom loop: the concept that organizations are spending lots of money on data systems without seeing improvements in data quality or efficiency.

Eira May

APIs have steadily become the backbone of AI systems, connecting data and tools seamlessly. Discover how they can drive scalable and secure training for AI models and intelligence automation.

Susi O'Neill